The contested meaning of “long COVID” – Patients, doctors, and the politics of subjective evidence jan 2022 ScienceDirect https://www.sciencedirect.com/science/article/pii/S0277953621009515
“What if - and hear me out because this isn't crazy - Long Covid turns out to be the new asbestosis or HIV/AIDS? Something which starts off looking fairly benign, but brews up into something really nasty. (Though it isn't even starting off benign, TBH.)” Thread: Discussion. -- Dr David Berger @YouAreLObbyLud https://twitter.com/YouAreLobbyLud/status/1516212680989679616
“1/ Let’s talk Long COVID: I’m grouping several important and interesting articles about the reality of Long Covid. By studying brain fluid, viral persistence and MRIs, we’re building our understanding of the “how” and “why” of this devastating malady.” Losts of images, infographics, and explanation. -- WesElyMD @WesElyMD 10 mar 2022 https://twitter.com/WesElyMD/status/1501717860942553089
“Whoa — new #LongCovid study — T cell death is worrisome… "These observations describe an abnormal immune profile in patients with COVID19 at extended time points after infection & provide clear support for the existence of a syndrome of LongCovid" ➡️Please please avoid COVID!” -- Dr Eric Feigl-Ding @DrEricDing 14 jan 2022 https://twitter.com/DrEricDing/status/1481722172695584772 Mild respiratory SARS-CoV-2 infection can cause multi-lineage cellular dysregulation and myelin loss in the brain “Not yet peer reviewed but from an outstanding team.” 7 jan 2022 https://www.biorxiv.org/content/10.1101/2022.01.07.475453v1 | Mild respiratory SARS-CoV-2 infection can cause multi-lineage cellular dysregulation and myelin loss in the brain Link to study; good thread Trisha Greenhalgh 11 jan 2022 https://twitter.com/trishgreenhalgh/status/1480852877828579330 SARS-CoV-2 infection and persistence throughout the human body and brain “Our data prove that SARS-CoV-2 causes systemic infection and can persist in the body for months.” dec 2021 Research Square https://www.researchsquare.com/article/rs-1139035/v1 How COVID-19 can damage the brain "Some people who become ill with the coronavirus develop neurological symptoms. Scientists are struggling to understand why." -- Michael Marshall 15 sep 2020 https://www.nature.com/articles/d41586-020-02599-5 “Coronavirus may be a vascular disease, which explains everything” https://elemental.medium.com/amp/p/2c4032481ab2
"Of all the papers that have come out on LongCovid so far, which do you think are the most important? Particularly around biomedical findings? If you could let every doctor know 10 things (backed by published papers), what would they be?" Thread - many links and infos. -- Hannah Davis @ahandvanish 26 feb 2022 https://mobile.twitter.com/ahandvanish/status/1497376814951542788 "If there are SARS-COV-2 fragments/proteins in LongCovid sufferers tissues, then how is anyone meant to get them out?" Thread - good and long discussion. -- Shaney Wright @ShaneyWright 23 feb 2022 https://mobile.twitter.com/ShaneyWright/status/1496525069467725832 "We hear a lot about all the tools we have to coexist with Covid. Well, I’ve had LongCovid for over 2 years now, and the only 'tools in my toolbox' available to manage it are the 3 B’s: Benadryl, Baby Aspirin, and a beta blocker. Before you risk repeated infections, think about this." Thread -- Laura Miers @LauraMiers 21 feb 2022 https://mobile.twitter.com/LauraMiers/status/1495509173987119105 Opinion: Long covid may unleash wave of health troubles after pandemic 20 feb 2022 The Washington Post https://www.washingtonpost.com/opinions/2022/02/20/long-covid-may-unleash-health-troubles-after-pandemic/ Understanding ME/CFS and Long COVID as post-viral conditions ME: Myalgic Encephalomyelitis CFS: Chronic Fatigue Syndrome https://duckduckgo.com/?q=ME+CFS+viral The Forever Disease: How Covid-19 became a chronic condition feb 2022 The New Republic https://newrepublic.com/article/161102/covid-19-long-haulers-chronic-disease-health-care "I hate making claims like this but I will: I believe reinfections can cause Long Covid, with its depleted subsets And sure, you can call that attrition." Thread on what is Long Covid "... repeated infection can put cells into a state of paralysis and even exhaustion." "Long covid is a state of persistent immune activation." "Many previously asymptomatic people would have no idea if they are on infection two, three or more." -- Anthony J Leonardi, PhD, MS @fitterhappierAJ 19 feb 2022 https://mobile.twitter.com/fitterhappierAJ/status/1494770759285280771 Antihistamines to treat long COVID: What you need to know Live Science 17 feb 2022 https://www.livescience.com/antihistamines-to-treat-long-covid-pasc COVID-19 and mitochondrial non-coding RNAs: New insights from published data "This persistent alteration in the expression of small mitochondrial RNAs might be involved in the long COVID syndrome and further studies are needed to confirm the possibility." See the following Introduction section for a good summary of 'post-viral fatigue syndrome', which has been known for decades. -- Andrea Pozzi 4 feb 2022 Physiology https://www.frontiersin.org/articles/10.3389/fphys.2021.805005/full Long Covid, holy crap! Screenshots of entire article from NYTimes. https://imgur.com/gallery/hGv30in https://www.nytimes.com/interactive/2022/02/19/science/long-covid-causes.html The risk of Long COVID "Long COVID is not a single ailment. It's a combination of a variety symptoms that cannot be explained in any other way but from a COVID infection. It can be caused by an acute infection, asymptomatic infection alone, or appear months after the infection. "Some folks who get it will never even know they had an infection." Lots of supported detail. -- Don Ford https://donford.substack.com/p/riskoflongcovid Zinc, Vitamin D, Specific Probiotics: Lactiplantibacillus plantarum CBD oil… Have all held up under test. "a low-inflammation diet" "You need sun and to walk outside. You cannot fully supplement the natural Vitamin D your body creates as a natural steroid." Immunological dysfunction persists for 8 months following initial mild-to-moderate SARS-CoV-2 infection: Study 13 jan 2022 Nature https://www.nature.com/articles/s41590-021-01113-x “1/ The problem with Myalgic Encephalomyeltis/Chronic Fatigue Syndrome MECFS is that it seems so ridiculous that exercise could actually make patients worse How can exercise be so bad for pwME but so good for almost every other serious illness?” Thread -- Dr Mark Guthridge @Dr_M_Guthridge 1 jul 2020 https://mobile.twitter.com/Dr_M_Guthridge/status/1278308004845109249 “All through this pandemic the fact of long term morbidity has been absent from public messaging and govt advice. @elizabethics is absolutely right - the public is ill informed and therefore can't be relied upon to make the right decisions.” -- @LongCovidSOS 23 dec 2021 https://twitter.com/LongCovidSOS/status/1473821790296281089 Don't be too cavalier about Omicron -- Long Covid is still a real risk "President Biden told the U.S. that if you’re triple vaxxed, you’re safe for the holidays. That’s not only not true, it’s dismissing almost 10 million Americans affected by a chronic disease." "... researchers behind a recent study published in the journal JAMA Network Open estimate that at least 50 percent of those who survive their initial illness go on to experience a number of physical, psychological, and neurological symptoms for a minimum of six months." -- Elizabeth Yuko 22 dec 2021 Rolling Stone https://www.rollingstone.com/culture/culture-commentary/covid-omicron-long-covid-risk-1274717/
Summary from what i have been reading:
Some percentage of people who get a Covid infection, with or without
symptoms, will live with symptoms anywhere from a few weeks, up to the number of
years we have known Covid.
I have read numbers from 10% to 50%.
One of the reasons for this is that this Covid things is all new,
and "Long Covid" is definitely new. So how it's measured will
depend on different scientists' definitions.
“There's a 1 in 10 chance if you get Covid you'll suffer Long Covid. You may not be able to make the stairs in one go due to COPD type symptoms,children have lost motor skills, others parts of memory. Worse you'll have organ damage or blood clots leading to stroke.
1 in 10.” Thread with experiences and links. -- @TigressEllie 2 jan 2022 https://twitter.com/TigressEllie/status/1477380948052295683 “Around 1 in 50 people in UK were reporting symptoms of Long Covid.” -- UK Office for National Statistics (ONS) 16 dec 2021 https://www.ons.gov.uk/peoplepopulationandcommunity/healthandsocialcare/conditionsanddiseases/articles/coronaviruscovid19latestinsights/infections#long-covid Long covid symptoms linger in 50 percent of people who survive the disease 12 nov 2021 The Washington Post https://www.washingtonpost.com/health/long-covid-50-percent-lingering-symptoms/2021/11/12/e6655236-4313-11ec-9ea7-3eb2406a2e24_story.html
“We're launching a new mini-series this week, a deep-dive into Long Covid. “Some people caught Covid in the first wave and simply never got better. Latest figures show 1.5million people in the UK now have Long Covid - and this could be the tip of the iceberg...” https://metro.co.uk/tag/long-covid/ 14 mar 2022 “Local surgeon — with decades of experience, in very high demand (>12-month waitlist), very physically fit (long-distance runner) — gets a mild case of Covid (never hospitalized), then abruptly retires due to persistent fatigue. Another face of "mild" Covid.” Thread of responses - many having post-viral fatigue after Covid. 14 jan 2022 https://twitter.com/DrHarryThomas/status/1481989232247951361 ‘Your body just stops’: long Covid sufferers face new ordeals as sick pay runs out 23 jun 2021 The Guardian https://www.theguardian.com/world/2021/jun/24/your-body-just-stops-long-covid-sufferers-face-new-ordeals-as-sick-pay-runs-out Comments and links re Long Covid as well as bad after-effects dec 2020 https://imgur.com/gallery/lUKSvNW
More people's experiences living with Long Covid are on the rewa experiences page.
Long Covid articles at Nature.com https://www.nature.com/search?q=long+covid&journal=